Course

Building a Simple Deterministic Model

This course is Part 5 of a 5-part course series designed for public health professionals, data scientists, epidemiologists, healthcare workers, policy makers, and anyone interested in infectious disease modelling, outbreak response, and gender-responsive data analysis.

Overview

This unit provides a comprehensive introduction to building and analyzing deterministic epidemiological models, with a focus on the 2016 Zika virus epidemic that affected Latin America and the Caribbean and was designated a Public Health Emergency of International Concern (PHEIC) by the World Health Organization.

Building upon foundational epidemic theory, you will develop a deterministic SIR-type model incorporating demographic factors to examine the interconnected dynamics of human-vector disease transmission. Through structured analysis of the relationships governing these interactions, you will translate conceptual disease dynamics into mathematical equations that form the foundation for computational simulation and analysis using the R programming language.

The unit emphasizes practical applications of key epidemiological concepts, including SIR model frameworks, herd immunity thresholds, and evidence-based control measures such as vector fumigation, insecticide-treated bed nets, and vaccination programs. Through case study analysis and model development, you will gain the quantitative skills necessary to assess epidemic impact and systematically compare intervention strategies to inform public health decision-making.

Learning Outcomes

  • Recognize how a simple deterministic model is built using ordinary differential equations.
  • Identify relevant parameters for modeling vector-borne disease (VBD) epidemics.
  • Learn how to create a diagram for a compartmental model
  • Translate mathematical equations for a deterministic model into R code.
  • Use model simulations to explore transmission scenarios and the potential impact of interventions.

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